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R,S-SULFORAPHANE, HIGH PURITY S8044

R,S-SULFORAPHANE, HIGH PURITY
Cas No. 4478-93-7
Purity ≥99%
S8044-25mg
S8044-50mg

Description

R,S-Sulforaphane is a synthetic isothiocyanate. R-Sulforaphane is the naturally-occurring isomer, found in broccoli. This compound exhibits antioxidative, neuroprotective, anti-inflammatory, anti-atherosclerotic, neuromodulatory, cardioprotective, anticoagulant, antibiotic, anticancer chemotherapeutic, and chemopreventive activities; research suggests that the R-isomer may be more bioactive than the S-isomer. R,S-Sulforaphane induces activity and expression of phase II enzymes, inhibits the aryl hydrocarbon receptor, and downregulates expression of HDACs and STAT5. In cellular and animal models of melanoma, this compound inhibits tumor growth and cell proliferation. R,S-Sulforaphane also induces autophagy. In animal models of Alzheimer’s disease, R,S-sulforaphane lessens cognitive impairment. Additionally, this compound increases activity of Nrf2 and expression of catalase, protecting against UV-induced oxidative damage in ex vivo models. In other animal models, R,S-sulforaphane inhibits TNF-α-induced adhesion of monocytes to epithelial cells and decreases levels of VCAM-1. In myocytes, this compound prevents angiotensin II-induced hypertrophy. Additionally, R,S-sulforaphane inhibits platelet aggregation by suppressing PI3K/Akt signaling. R,S-Sulforaphane also displays antibacterial efficacy against Escherichia. Please note: This compound is a neat liquid at room temperature, clear to slightly yellow in color. It is not dissolved in solvent. In small quantities the material will coat the sides of the ampule it is shipped in and may appear to be invisible, or it may be trapped in the tip of the ampule. Wash the upper and lower parts of the ampoule with solvent to ensure all of the material is obtained.

Product Info

Cas No.

4478-93-7

Purity

≥99%

Formula

C6H11NOS2

Formula Wt.

177.29

Chemical Name

1-Isothiocyanato-4-(methylsulfinyl)-butane

IUPAC Name

1-isothiocyanato-4-methylsulfinylbutane

Synonym

D,L-Sulforaphane, Sulforaphane, 4-(Methylsulfinyl)-butyl isothiocyanate​​

Solubility

Soluble in ethanol, methanol, or ethyl acetate. Miscible with water and/or DMSO.

Appearance

Slight yellowish liquid

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

S8044 MSDS PDF

Info Sheet

S8044 Info Sheet PDF

Brochures

Sulforaphane Flyer

 

Natural Products Booklet