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RADICICOL R0212

RADICICOL
Cas No. 12772-57-5 
Purity ≥96%
R0212-1 mg
R0212-5mg

Description

Radicicol is an analog of benzoquinone ansamycin that inhibits HSP90, Src family kinases, and Raf. Radicicol exhibits neuroprotective, antibiotic, antifungal, anti-parasitic, and antimalarial activities. In Plasmodium, radicicol targets topoisomerase VI-B, inhibiting mitochondrial replication. Radicicol also increases survival and neurite outgrowth of neurons in chick embryos.

Product Info

Cas No.

12772-57-5

Purity

≥96%

Formula

C18H17ClO6

Formula Wt.

364.78

Chemical Name

8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihyroxy-14- methyl-6H-oxireno[e][2]benzoxacyclotetradecin- 6,12(7H)-dione

Synonym

Monorden, Monorderne

Melting Point

193.5°C

Solubility

Soluble in DMSO, methanol or ethanol.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

R0212 MSDS PDF

Info Sheet

R0212 Info Sheet PDF