SIRT7 inhibitor 97491试剂

SIRT7 inhibitor 97491
Based on 2 reference(s) in Google Scholar
Axon 2968

CAS [1807758-81-1]

MF C15H12ClN3O
MW 285.73

Purity: 99%
Soluble in DMSO

Description

SIRT7 inhibitor 97491 decreased SIRT7 activity in a dose-dependent manner (IC50 value of 0.325 μM). SIRT7 inhibitor 97491 induced expression of p53 and its acetylation by inhibited SIRT7. Moreover, SIRT7 inhibitor upregulated apoptotic effects through the caspase related proteins and inhibited cancer growth in vivo.

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