InVivoMAb anti-mouse NK1.1 BE0036

InVivoMAb anti-mouse NK1.1
BE0036-1mg
BE0036-5mg
BE0036-25mg
BE0036-50mg

About InVivoMAb anti-mouse NK1.1

The PK136 monoclonal antibody reacts with mouse NK1.1 also known as CD161b/CD161c, KLRB1, NKR-P1A and Ly-55. NK1.1 is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by the Klrb1c/NKR-P1C gene. NK1.1 plays roles in NK cell activation and differentiation, IFN-γ production, cytotoxic granule release, and is thought to be involved in the generation of Th2 cells. NK1.1 is predominantly expressed as a disulfide-linked homodimer on NK cells however, it is also expressed on NK-T cells, a rare population of T lymphocytes. NK 1.1 is only expressed by C57BL/6, FVB/N, and NZB strains of mice and not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129 strains.

InVivoMAb anti-mouse NK1.1 Specifications

Isotype	Mouse IgG2a, κ
Recommended Isotype Control(s)	InVivoMAb mouse IgG2a isotype control, unknown specificity(BE0085)
Recommended InVivoPure Dilution Buffer	InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen	Mouse spleen and bone marrow cells enriched for NK1+ cells
Reported Applications	in vivo NK cell depletion Flow cytometry
Endotoxin	<2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay
Purity	>95% Determined by SDS-PAGE
Formulation	PBS, pH 7.0 Contains no stabilizers or preservatives
Sterility	0.2 μM filtered
Production	Purified from tissue culture supernatant in an animal free facility
Purification	Protein A
Storage	The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
RRID	AB_1107737
Molecular Weight	150 kDa

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