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PD 0325901 Axon 1408

PD 0325901
Axon 1408

CAS [391210-10-9]

MF C16H14F3IN2O4
MW 482.19

Purity: 99%
Optical purity: >98% ee
Soluble in DMSO

Description

Potent, highly specific non-ATP-competitive inhibitor of MEK (aka MKK) 1/2; a derivative of CI-1040 (Axon 1368) to improve bioavailability; clinical candidate and highly recommended tool to inhibit MKK1 or MKK1 plus MKK5 in cells.
* PD 0325901 and CHIR 99021 (Axon 1386) from Axon Medchem are often used together as perfect 2i in stem cell research (Axon 2128).

*Promotion: PD 0325901 is also part of Inhibitor Set(s):

Axon 2128 Axon 5009 Axon 5010 Axon 5011

 

Prime Source Information: 
PD 0325901 from Axon Medchem has been procured by many labs as drug standard for generating reliable and reproducible biological data, evidenced by many recent publications.

KEYWORDS: PD 0325901 | supplier | MEK1 inhibitor | PD0325901 | PD325901 | CAS [391210-10-9] | MAPK | MEK1 | MEK2 | Inhibitor | MKK | MKK1 | stem cell | pluripotent | renewel | DNA | lesion